Developmentally regulated alternative splicing of chDab1Fulllength chDab1 cDNA encoding a predicted open reading frame of 535 aa was obtained by screening an ED7 chick retina cDNA library with the 532 bp DDPCR DNA fragment (Figure 2). Overall, the chicken Dab1 protein sequence had a high level of similarity to the 555 aa human and mouse sequences (92% identical; 96% similar), with two major differences: (i) a deletion of 105 bp (35 aa) located immediately after aa 186 and corresponding to aa 187 of human/mouse Dab1, and (ii) an insertion of 57 bp (19 aa) located after aa 206. Based on the exon/intron structure of human Dab1 genomic DNA, the 105 bp deletion region corresponds to two exons (exons 7 and 8) and the 57 bp insertion region corresponds to a single exon (exon 92) (Bar et al, 2003).It is up to individual businesses to decide whether or not to add the fee. They also need to disclose it to consumers. History.

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