Now Carine Roitfeld gets hers. "Mademoiselle C" picks up with the fashion editor/stylist/image maker she still doesn't quite know what to call herself in the wake of her resignation from Vogue Paris, where she served as editorinchief for 10 years. She's embarked on a new adventure: to launch her own magazine, CR Fashion Book, in New York..Bystander activation describes a nonantigenspecific activation of T or B cells usually mediated by soluble inflammatory products of nearby immune cells.AntiMyelin AntibodiesImmunoglobulins produced by activated B cells in the CNS and CSF target numerous selfantigens including components of the CNS myelin such as myelin basic protein, proteolipid protein, myelinassociated glycoprotein, and myelin oligodendrocyte glycoprotein.67, 68 A great number of papers discusses the involvement of myelinspecific antibodies in the development of demyelination and disease progression.69, 70 Pros and cons for the primary pathogenic significance or the re